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Aripiprazole is classed as an atypical (second-generation) antipsychotic. It works at a large number of sites, including receptors and transporters. The drug mediates its action by either blocking receptors (antagonist) or by binding to them and inducing an opposite response to receptor’s normal role (inverse agonist). Aripiprazole exerts its impact via various receptors including multiple subtypes of serotonin, dopamine, adrenergic, muscarinic acetylcholine and histamine receptors. It also works on serotonin, norepinephrine and dopamine transporter proteins. The drug was first approved by the US Food and Drug Administration (FDA) for use in schizophrenia in 2002.

Other names for this medication:
Aripiprazole, Abilify, Abilitat,

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Aripiprazole is used to treat certain mental/mood disorders (such as bipolar disorder, schizophrenia, and irritability associated with autistic disorder). It may also be used in combination with other medication to treat depression. Aripiprazole is known as an antipsychotic drug (atypical type). It works by helping to restore the balance of certain natural chemicals in the brain (neurotransmitters). This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. Aripiprazole can treat severe mood swings and decrease how often mood swings occur.

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Chronotherapy of high-dose active Vitamin D(3): is evening dosing preferable? Predictors of late aortic events after Stanford type B acute aortic dissection. CO2 is also delivered to the bacterium where it enters the Calvin-Benson cycle. 18:1 levels in ssi2 plants were increased by performing epistatic analyses between ssi2 and several mutants in FA pathways that cause an increase in the levels of 18:1 in specific compartments of the cell. Emergency drainage for decompression of the renal collecting system was performed for empirical treatment in cases of failure of initial treatment and for severe cases.

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The data from this study support the notion that some aspects of auditory learning and temporal resolution may be preserved in the elderly. Long-term effect of alpha-glucosidase inhibitor on late dumping syndrome. Diabetes or prediabetes in newly diagnosed patients with nonaffective psychosis?

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Previous experience of the common infectious diseases of immunisation and of tonsillectomy in a group of school children. Development of fibroblast-seeded collagen gels under planar biaxial mechanical constraints: a biomechanical study. Health status and health behaviour as predictors of the occurrence of unemployment and prolonged unemployment.

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Historically, pain has been poorly managed in the pediatric emergency department (ED) (PED), resulting in measurable psychosocial issues both acute and delayed. Two new potential antifungal coumarin glycosides, 6-chlorocoumarin 7-O-beta-D-glucopyranoside (1) and 7-hydroxy-4-trifluoromethyl-coumarin 5-O-beta-D-glucopyranoside (2), were synthesized via enzyme-mediated glycosylation of the respective aglycone, 6-chloro-7-hydroxycoumarin and 5,7-dihydroxy-4-trifluoromethylcoumarin, using transgenic hairy roots of Polygonum multiflorum. Alterations observed in haptoglobin reflected the disease process better than those in AGP. Children affected by celiac disease exhibit an enhanced sympathetic tone, persisting after 24 months of GFD whereas gastrointestinal and systemic symptoms disappear.

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Historically, the major European river systems contained different, evolutionarily distinct trout lineages, and some of this genetic diversity has persisted in spite of extensive human-mediated translocations. Field procedures in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Vibrational relaxation pathways of AI and AII modes in N-methylacetamide clusters.

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Brain reinforcement system function is ghrelin dependent: studies in the rat using pharmacological fMRI and intracranial self-stimulation. Proton pump inhibitors are effective for the treatment of gastric ulcers after endoscopic submucosal dissection (ESD). Symmetrical arterial occlusion of upper extremities head, and neck: a rare syndrome. NFK- and Kyn-containing peptides displayed an intense signal at m/z 174.1, which could be useful in identifying accordingly modified peptides by a sensitive precursor ion scan.

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Scavenger receptor A deficiency accelerates cerebrovascular amyloidosis in an animal model. Here we show that FG-mediated neurotoxicity and ERK1/2 phosphorylation in neuronal cultures is significantly attenuated by activation of metabotropic glutamate receptor 5 (mGluR5) but not mGluR2.

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Among influenza viruses, type A viruses exhibit the greatest genetic diversity, infect the widest range of host species, and cause the vast majority of cases of severe disease in humans, including cases during the great pandemics. Themes related to contraception and sexual partners were analyzed.

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The role of ovarian hormones and nitric oxide on morphine-induced antinociception and their interaction have been widely investigated. Consequently, the ethoxide-hydroxide intermediate is decomposed into ethene through hydrogen abstraction from the ethoxide methyl carbon to either the OH group of hydroxide or the oxygen of the ethoxide group with high activation energies of 64.8 and 63.5 kcal mol(-1), respectively. Cyst-forming intraductal papillary neoplasm of the bile ducts: description of imaging and pathologic aspects. ERK1/2 pathway is activated in degenerated Rpe65-deficient mice. We report for the first time Erbium doped Tellurium dioxide single-mode planar rib waveguide amplifiers with net fiber to fiber gain and wide bandwidth operation.

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