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Karum (Clopidogrel)
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Clopidogrel

Karum is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Karum is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial disease. It has been shown to be superior to aspirin in reducing cardiovascular outcomes in patients with cardiovascular disease and provides additional benefit to patients with acute coronary syndromes already taking aspirin. Karum was granted FDA approval on 17 November 1997.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Karum is an antiplatelet medicine, or blood thinner. It makes your blood flow through your veins more easily.

This means that your blood will be less likely to make a dangerous blood clot.

Taking Karum helps prevent blood clots if you have an increased risk of having them.

Your risk is higher if you have or have had:

  • a heart attack
  • unstable angina
  • a stroke or "mini-stroke" (transient ischaemic attack or TIA)
  • peripheral arterial disease
  • an operation on your heart or blood vessels, such as a coronary stent insertion

Karum comes as tablets and is only available on prescription.

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Adult neural stem cells (ANSC) dissociated from the adult mouse hippocampus were expanded in culture with basic fibroblast growth factor (BFGF) and epidermal growth factor (EGF). There was no restriction on date, language or publication status of RCTs. Unlike catalase and mannitol, superoxide dismutase inhibited agonist-induced platelet CD40L expression in healthy subjects. Southern Section Interdisciplinary Beef Cattle Symposium: Forage and co-product systems for stockers in the South: have fundamental shifts in markets changed the optimal system? In this paper, we provide evidence that cullin deneddylation is not intrinsically coupled to substrate polyubiquitination as part of the CRL activation cycle.

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The Poisson regression was used to estimate the excess relative risk (ERR) per unit of cumulative exposure to plutonium and external gamma-ray. Protein-protein interactions on weak-cation-exchange sorbent surfaces during chromatographic separations. Following a diagnosis of nocardiosis, made based on sputum culture, the patient was treated with trimethoprim/sulphamethoxazole and then, due to treatment side effects, with minocycline. Characterization of the large (L) RNA of peanut bud necrosis tospovirus. The rate of collagen fibril formation and its quantity, measured as increased turbidity, was markedly increased by the presence of TNX, whereas type VI collagen did not increase the quantity but accelerated the rate of collagen fibril formation.

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Polarity inversion of bioanode for biocathodic reduction of aromatic pollutants. A double-blind placebo-controlled trial of UVA-1 in the treatment of dyshidrotic eczema. In Escherichia coli, the origin of DNA replication, oriC, becomes transiently hemimethylated at the GATC sequences immediately after initiation of replication and this hemimethylated state is prolonged because of its sequestration by a fraction of outer membrane. Influence of transition metals on Streptomyces coelicolor and S.

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Both studied human subunit vaccines failed to protect and to stop viral shedding with no evidence of serological reaction against rH3N2. Pseudo attP sites in favor of transgene integration and expression in cultured porcine cells identified by Streptomyces phage phiC31 integrase. HM and LP resulted in better glycaemic control than HR during the observation period. Studies using recombinant fibrillin fragments indicate that an interaction between the N- and C-terminal regions drives head-to-tail assembly. Dynamic finite element analysis of impulsive stress waves propagating from distal end of femur.

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Nascimento, DDS, MS, PhD PURPOSE/QUESTION: The study sought to determine whether the use of preventive and restorative therapies based on individual caries risk for 2 years could reduce caries increment compared to traditional dental care provided at the University of California, San Francisco School of Dentistry (UCSF) SOURCE OF FUNDING: The main research support was provided by NIH/NIDCR and the oral products used in the study were provided by Proctor and Gamble, Omnii Oral Pharmaceuticals and Oral B TYPE OF STUDY/DESIGN: Randomized controlled trial We propose that SDS is now a candidate microbicide for formulation and testing with humans. In addition to T cell response, we also annotate peptides that are naturally processed HLA binders, e.g., peptides eluted from HLA in mass spectrometry studies. Were all men with this problem to seek medical help there would be a large burden on healthcare systems.

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Uveitis (intraocular inflammation) is a potentially blinding group of, probably autoimmune, conditions predominantly occurring in the working age group. It was reported that electroacupuncture (EA) has analgesic effect on neuropathic pain, and the analgesic effect was mediated by the endogenous opioid peptides.

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Pharmacological treatment of Attention-Deficit/Hyperactivity Disorder may be associated, at least in some cases, with adverse cardiovascular events, including clinically significant elevation in heart rate and systemic blood pressure. Laparoscopic versus open adrenalectomy: another look at outcome using the Clavien classification system. Multimodal brain monitoring is an important approach to gain insight into brain function, modulation, and pathology. Guanfacine modulates the influence of emotional cues on prefrontal cortex activation for cognitive control. In this study, we investigated the effects of NPF and its receptor-neuropeptide F receptor (NPFR1) on Drosophila sleep.

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Promising new findings report high diagnostic accuracy for metabonomic and epigenetic approaches as well as combinatorial functional neuroimaging approaches, which are currently representing the forefront of MDD biomarker development. We examined 29 first-episode schizophrenic patients admitted at an Army Medical Center within 10 days of psychosis onset, using the Neurological Evaluation Scale and the 18-item Brief Psychiatric Rating Scale (BPRS) and compared them to controls. Although severe acute hyponatremia following coronary angiography is rare, potentially lethal neurologic manifestations may result. Much knowledge into protein folding, ligand binding, and complex formation can be derived from the examination of the nature and size of the accessible surface area (SASA) of the polypeptide chain, a key parameter in protein science not directly measurable in an experimental fashion. Scientific evidence on the legalization of abortion in Mexico City

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Eighteen patients with atopic dermatitis (AD) and 6 patients with chronic plaque-type psoriasis as well as 14 healthy control subjects. Predictors of OA that were explored included patient age, sex, body mass index (BMI), smoking status activity level, meniscectomy before or concurrent with ACL reconstruction, chondral injury present at the time of ACL reconstruction, graft type and source, tibial and femoral tunnel positions, need for revision, and length of follow-up. We analyzed the utilization, costs, and proportion of injections in the insured market for oral-injection dual-dose-form ingredients (DFIs).

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Sequence comparisons of bacterial ribosomal RNA gene hypervariable regions isolated from para que sirve alprazolam 0.50 mg beach sands located to the east and west of Mobile Bay in Alabama demonstrated that regional drivers account for markedly different bacterial communities. Constitutively activated STAT3 in normal human esophageal epithelium cells (HET-1A) elevated Oct-1 expression,and promoted proliferation and decreased apoptosis. In addition, we investigated the regulation of PA accumulation in developing A. Statistical analysis and classification/regression experiments further suggest that the derived features can differentiate between multiple arousal levels and stress-eliciting environments for two datasets.

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Potential fitness benefits of group living in the red fox, Vulpes vulpes. To investigate the expression of myofibrillogenesis regulator-1 (MR-1) in relation to clinicopathological parameters and postoperative survival in a group of Chinese patients with gastric cancer. The purpose of the present study was to find out whether a series of terrorist attacks, which share some common features, elicit flashbulb memories (of the personal circumstances in which the person first learned about these dejac 30 tablet free events) that are usually elicited by a single, unexpected, surprising, and personally important event. Dental caries was detected in only 3 children in the last visit (at 30 months), who presented significantly higher SM scores than the children without caries in the same visit.