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Aldactazine (Spironolactone)

Aldactazine is indicated in patients with congestive heart failure. It is a competitive aldosterone antagonist that increases sodium excretion while reducing potassium loss at the distal renal tubule. This mechanism of action means that hyperkalaemia can occur, particularly in patients with impaired renal function. Aldactazine should not be used in patients with severe renal impairment or pre-existing hyperkalaemia.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Aldactazine is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks. Aldactazine is also used to lessen the need for hospitalization for heart failure.

Aldactazine is also used to diagnose and treat hyperaldosteronism, a condition in which the adrenal gland produces too much hormone called aldosterone. This medicine may also be used to treat fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome.

Aldactazine is a potassium-sparing diuretic (water pill). It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. This medicine is also used to treat or prevent hypokalemia (low potassium levels in the blood).

This medicine is available only with your doctor’s prescription.

This product is available in the following dosage forms:

  • Tablet
  • Suspension

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In this study, we compared the effectiveness of serum levels of liver-specific or -enriched miRNAs (miR-122, miR-192, and miR-194) with that of conventional hepatic biomarkers (alanine aminotransferase (ALT) and aspartate aminotransferase (AST)) as biomarkers for nSP70. Feedback from clinical incident reviews closes the loop of the review process and creates a platform for necessary changes to be undertaken.

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Why shared data should not be acknowledged on the author byline. A novel low molecular weight antagonist of vascular endothelial growth factor receptor binding: VGA1155. Whereas NO fluxes obtained from the tunnel measurements were generally small and at a typical background level, the chamber measurements revealed high spatial and temporal variability of NO emissions, including slight NO uptake and precipitation-triggered emission peaks.

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This review highlights recent advances regarding how the cooperation of Rho effector Rhotekin and S100A4 suppresses stress fiber generation to permit RhoA-mediated lamellae formation. The patients were recalled at 1 week, 3 and 6 months after surgery for clinical assessment and measuring the bone density via CBCT at a region of interest (ROI) including the fracture line. To evaluate the drug profile of patients attending general dental practice and to assess the significance of this for the provision of dental care. Extending prior findings in clinical populations, results indicate that lower PM functioning is uniquely associated with mild, concurrent IADL problems in healthy older adults.

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Evaluation of peripheral and central nerve integrity in hemodialysis and renal transplantation. We use a three-stage technique consisting of infiltration, ultrasound-assisted sculpturing, and suction-assisted liposuction. Themes that emerged from the interviews regarding the strengths and weaknesses of and ways to improve the program. We hypothesized that the delivered doses correlate better with parotid salivary output than the planned doses, used in all previous studies, and that determining these correlations will help make decisions regarding adaptive radiation therapy (ART) aimed at reducing the delivered doses.

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The preoperative relationship between pulmonary arteriolar resistance index and RV forward stroke work index, that is, RV systolic function to pressure afterload, might predict a postoperative fate of the right heart function. Antioxidant status and peroxidative stress in mother and newborn -A pilot study. The I of the storm-relations between self and conscious emotion experience: comment on Lambie and Marcel (2002). Addition of this substrate to induced and noninduced cell culture populations allows for the rapid site-specific detection of caspase up-regulation without the requirement for a wash step. As BiP protected CT from aggregation it is proposed that BiP maintains CT in a soluble, export-competent state.

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Bivariate analysis followed by odds ratios calculation indicated that subjects with waist circumference above the proposed cutoff points have increased chances of presenting cardiovascular disease risk factors. The addition of purified prothrombin, but not of factors X or VIIa, to normal plasma caused a concentration-dependent, TAFI-mediated inhibition of fibrinolysis.

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Consequently the transition from optical thicknesses for which contrast is above the contrast threshold at all spatial frequencies to optical thicknesses for which contrast is below the threshold at high frequencies is sufficiently gradual to permit fuzziness of the Sun to be observed through clouds of constantly changing opt cal thickness. There was no effect of TO, in two doses, on pulse and blood pressure and no side effects in acute tolerability study on Day 1. In general, interactions between trace elements in this study were similar to those found in polluted areas or in experimental studies in animals receiving diets containing high levels of toxic metals or inadequate levels of nutritional essential elements. This article aims to explore spiritual care in the neonatal care environment in addition to highlighting the importance of spiritual leadership of a health team in that context.

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Production of human metabolites of the anti-cancer drug flutamide via biotransformation in Cunninghamella species. In this article, we propose and investigate the automatic design of decision-tree induction algorithms tailored to particular drug-enzyme binding data sets. green fluorescent protein) was coupled to the transcription of an essential gene (e.g.

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AICRG, Part I: A 6-year multicentered, multidisciplinary clinical study of a new and innovative implant design. Doripenem was as effective as imipenem and meropenem in our study. We assess the functional importance of a colorectal valve in patients with rectal urinary diversion.

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We used a recently published method for generating reduced two-compartment models that retain the asymmetric coupling of anatomically reconstructed motor neurons. Severe cholestasis is one of the important causes of prolonged hospitalization in patients with acute hepatitis A. In this review, we point to issues that arise in discriminating the effects of these concurrent processes from those of the parser/interpreter in neural measures and to approaches that may help resolve them.

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Estimation of the risk of upper digestive tract bleeding in patients with portal cavernomatosis The influence of smoking on the natural history of HPV infection in men is not well understood. Using this approach, we have identified and cloned a novel genomic fragment which is co-amplified with N-myc in neuroblastomas. The seasonal variations of respiratory syncytial virus infections in Turkey: a 2-year epidemiological study.

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However, when bacteria and Zn are preassociated on entering the column, zinc transport is initially facilitated. The constellation of symptoms and findings in narcolepsy are reviewed together with diagnostic testing and therapy, Parasomnias, including sleep terrors, somnambulism, and rapid eye movement (REM) behavior sleep disorders are described, together with associated laboratory testing results and treatment. To obtain a rapid, efficient and mild synthesis of 5,5-diphenylhydantoin and 5,5-diphenyl-2-thiohydantoin derivatives, ultrasonic irradiation has been applied to the reaction mixtures containing substituted benzils and urea or thiourea derivatives catalyzed by KOH in DMSO/H(2)O, which allowed us to achieve products at room temperature in a good yield and short time without any side product.

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Our paradigm provides insight into higher-order processing related to language comprehension and reasoning in healthy subjects. Orlando Regional Healthcare System, 5D11-3727 FLCA5 (9/21/2012)-FL.

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Injection of (S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester (ISO-1, 100 nmol), a MIF antagonist, significantly attenuated these NMDA-induced responses. Reproductive health awareness among educated young women in Egypt. Acute stimulation of the hypothalamo-pituitary-adrenal (HPA) axis by selective serotonin reuptake inhibitors (SSRIs) is mediated by several postsynaptic 5-HT receptor subtypes.

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Common (e.g., availability of pocket money, more time spent with friends, poor parental monitoring, poor school bonding, bullying others, and lower risk perception of substance use) and unique predictors (e.g., school achievement on national tests) were identified. Preliminary report of the evaluation of the gametocytocidal action of bulaquine, in adult patients with acute, Plasmodium falciparum malaria.

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Pragmatic language behaviors of adults diagnosed with chronic schizophrenia. NAD(P)H oxidase and eNOS play differential roles in cytomegalovirus infection-induced microvascular dysfunction. However, there is no specific report documenting the effect of intraoperative traction on the correction of AIS. Outbreak of severe rotavirus gastroenteritis among children--Jamaica, 2003.

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Relationship of periodontal disease and edentulism to stroke/TIA. Current advances in chemotherapy provide opportunities for stage IV gastric cancer patients with distant metastasis to undergo potentially curable resection. Here we report the mapping of a 42-amino acid segment (N42) at the N-terminus of DAZAP1 that is both necessary and sufficient for its transcription-dependent nuclear localization. Biomarkers predictive of pathological complete response (pCR) to neoadjuvant chemotherapy (NACT) of breast cancer are urgently needed. The histological and quantitative PCR detection of Lawsonia intracellularis were correlated in pigs with diarrhoea.

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Surveillance in Mexico is based on the detection of Influenza-Like Illness (ILI) and antiviral treatment should begin within 48 hours to avoid the main complication, pneumonia. Prolonged and regionally progressive symptomatic cerebral hyperperfusion syndrome after superficial temporal artery-middle cerebral artery anastomosis in a patient with moyamoya disease. In addition, improvements to the cellobiohydrolase I activity period substantially improved overall glucose production. Here we investigated theoretically the joint effects of recombination and self-fertilization on base composition, and tested the predictions with genomic data from the complete A.

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Group A consisted of 35 patients who underwent isolated ACL replacement and whose rehabilitation protocol included early motion. Estimation of estrogenic and antiestrogenic activities of selected pesticides by MCF-7 cell proliferation assay. Right-sided arcus aorta (RSAA) is a rare congenital anomaly that may cause chronic cough and dyspnoea. It is likely that many factors contributed to these observed differences, including variations in the population undergoing patch testing, variations in allergen exposure, and variations in climate.

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Functional characterization of genetic polymorphisms identified in the promoter region of the xanthine oxidase gene. Prevalence of epicondylitis, rotator cuff syndrome, and low back pain in Latino poultry workers and manual laborers. Modulation of RNA editing by functional nucleolar sequestration of ADAR2.

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Antimicrobial creams and other dressing agents used for traumatic wounds are ineffective in deep burns with eschar. Two new technologies (tissue microarrays (TMAs) and proteomics) have generated a great amount of data in life science. To compare the visualization of the target gastric varices (GV) on balloon-occluded retrograde transvenous venography (BRTV) using iodinated contrast material vs carbon dioxide (CO(2)) in preparation for subsequent balloon-occluded retrograde transvenous obliteration (BRTO) using foam sclerotherapy. alpha2beta1 integrin is crucial for stress fiber formation, whereas GPVI triggers rapid and sustained activation of the Erk1/2 pathway. The sensitivity of this method was demonstrated on the separation of farnesol directly from the cultivation medium.

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Relatively high numbers of gamma delta T cells--predominantly, V gamma 9V delta 2 T cells--were detected only in the T cell lines of the patients with GH. The factors generated correlated strongly with the dimensions and confirmed the empirical process mathematically. These studies pave the way for the investigation of ROS-inducing copper(ii) complexes as prospective antiproliferative agents in cancer chemotherapy. Declining susceptibilities of gram-negative bacteria to the fluoroquinolones: effects on pharmacokinetics, pharmacodynamics, and clinical outcomes.

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By using well-designed microchannels with different channel widths and depths, the propagation velocity was successfully controlled based on two independent effects: (i) a transition in the proton diffusion mode and (ii) the formation of a slanted wave front. The associations between musculoskeletal complaints and possible predictors were analyzed by binary logistic regression.

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Iteratively conducted usability tests demonstrated an increased ease of use from the first to the last version of the website through significant improvement in the percentage of unproductive clicking along with fewer questions asked about how to use the program. The effects of pregnancy intention on the use of antenatal care services: systematic review and meta-analysis. This might provide a basis for clinical application of perivenous support. The complementarity of NMR and X-ray crystallography for biomacromolecular studies has been particularly evident in analysis of transcription factor structures and interactions. This study describes and analysis five years of experiences from organising an interorganisational project on vocational rehabilitation.

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Improved tuberculosis smear detection in resource-limited settings: Combined bleach concentration and LED fluorescence microscopy. The CSF IL-6 levels are increased in patients with VD, suggesting that inflammatory mechanisms may be involved in the development of cognitive decline in some patients with cerebrovascular disease. Inflammatory and immunological responses have been found to be decreased and bone formation is found to be increased in immunosuppressed animals. Therefore, the vibration damping in the tissues must have increased. Endomyocardial fibrosis is a restrictive cardiomyopathy of unknown etiology prevalent in tropical regions.

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No meta-analysis was conducted due to lack of similarities across the included studies. In these processes, solid boundaries both influence and are shaped by the surrounding fluid, but the emergence of morphology as a result of this interaction is not well understood. The results underscore the need to consider multiple forms of maltreatment, as well as severity, when making inferences regarding potential effects on later functioning. Measurement of dynamic end-to-end cavity phase shifts in cesium-fountain frequency standards.

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These fixations were tested to failure with a three-point bending cyclic loading protocol using an electromechanical microtester and a 1 kN load cell. This paper presents the results of a detailed field investigation that was performed for studying groundwater recharge processes and solute downward migration mechanisms prevailing in the unsaturated zone overlying a chalk aquifer in Belgium. The addition of the robot such as the de Vinci surgical system could make some of the extracervical approaches technically less challenging and improve patient outcomes. These findings suggest that PPA not only could be developed into a novel agent that can detect drug resistant cancer cells and predict chemotherapy outcome, but also it has potential value in immunotherapy against drug resistant cancer cells through inducing the tumoricidal activity of macrophages. The novel approach of the research encourages empathy with individual users and allows generic abilities, such as bending, reaching and lifting to be assessed.

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The activator interacted with alphaCTDAt with kinetics and affinities similar to those of the full-sized -subunit. It is hypothesized that a waiting period allows the myocardium to recover prior to revascularization, thus decreasing morbidity and mortality.

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We have cloned the wild-type LF3 gene and characterized a hypomorphic mutant allele of LF3. To investigate the optimum proportion of Mosaicplasty and genes-enhanced tissue engineering for the repair of acute osteochondral defects. Teicoplanin has been reported to have a lower adverse drug reaction (ADR) rate than vancomycin. Brevibacillus brevis X23 is an appropriate biocontrol agent against bacterial wilt caused by Ralstonia solanacearum.

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In patients with this disease, altered glycan structures in the unique hinge region of the heavy chains of IgA1 molecules lead to the exposure of antigenic determinants, which are recognized by naturally occurring antiglycan antibodies of the IgG and/or IgA1 isotype. However, this response is terminated prior to the onset of clinical symptoms in the infected hippocampus, seemingly pointing to a critical juncture in the disease.

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Based on this case, our understanding of these rare tumors and their clinical course is deepened. Health Libraries and Information Services in Tanzania: A Strategic Assessment. Osmoprotection of Bacillus subtilis through import and proteolysis of proline-containing peptides. Physical medicine and rehabilitation department at a university hospital. We found that, while there was no significant sex by ethnicity effect for TCRA, men were significantly more likely than women to endorse TCRA and the Korean group had significantly higher TCRA than the Japanese group.

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Diagnosis is made histopathologically by fine needle biopsy after the elimination of malignancy. We showed that the discrepancy between pre-sCr and pre-CysC could predict improvement of renal function after intervention in patients with postrenal AKI. The use of photodynamic therapy in the treatment of lentigo maligna. GH stimulation tests: evaluation of GH responses to heat test versus insulin-tolerance test.

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Of particular interest are the MEK or MAP2K (mitogen-activated protein kinase kinase), phosphatidylinositol-3 kinase (PI3K) and signal transducer and activator of transcription-3 (STAT3) pathways. The sensitivity, specificity, positive predictive values and negative predictive values of the traditional selective approach were calculated compared to universal rapid screening. Threonyl-tRNA synthetase (ThrRS) participates in protein synthesis quality control by selectively editing the misacylated species Ser-tRNA(Thr). This novel mechanism of immune potentiation may be exploited for development of adjuvants for genetic vaccines against infectious pathogens and cancer.

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This paper analyses the contribution of chest injuries to the outcome of head injuries in the University of Nigeria Teaching Hospital (UNTH) and the Memfys Hospital for Neurosurgery (MHN) in Enugu, Nigeria. The diagnosis of disseminated demyelinating disease of central nervous system (DDD CNS) was established on clinical criteria, cerebrospinal fluid (CSF) analyses, electrophysiological and neuro-radiological examinations. In so doing, candidates across the board will feel and think in a more collegial manner, and may find that learning psychoanalysis is to learn something new and exciting.

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Adolescents in families hampered by anxiety and depression symptoms are at a substantially higher risk of medical welfare dependence in young adulthood. No author has a financial or proprietary interest in any material or method mentioned. Effects of a signaled delay to reinforcement in the previous and upcoming ratios on between-ratio pausing in fixed-ratio schedules. We have shown here aberrant biological responses mediated by the TLR3 variant receptor, L412F, which may explain clarithromycin dose for infants in part susceptibility of patients to chronic candidiasis, viral infections and autoimmunity.

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Amelioration of hyperoxia-induced lung injury using a sphingolipid-based intervention. Traditional healing systems have become of increasing interest as many people believe that they can be used without any risk and side effects. As was evident from several previous studies, dispersion modeling in such areas of complex terrain and, moreover, with frequent what does cipex tablets download calm wind conditions, is difficult to handle.

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A number of human diseases result from mutations in mtDNA-encoded proteins, a group of proteins that are hydrophobic and have multiple membrane-spanning regions. The responses were not influenced by the pretreatment with L-365,260, a type B CCK receptor (CCKBR) antagonist, while they were significantly diminished by pretreatment gastronorm trays uk weather with MK-329, a CCKAR antagonist.

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Remitted and first-episode schizophrenia patients taking haloperidol were given adjunct VPA for approximately 2 weeks and tested using a measure of clinical symptoms (Positive and Negative Syndrome Scale) and saccadic eye movement tasks over three testing periods. Gene cloning and characterization of a solvent-resistant glucose dehydrogenase from Bacillus sp. Selection-induced variation at the pantophysin locus (PanI) in a Norwegian fjord population of cod (Gadus morhua L.). Clinical application of azithromycin extended-release (ER) formulation to treat female sexually transmitted infection Results of this interim analysis suggest treatment of DFUs with a UBM could significantly reduce the vilerm dosage for benadryl time to healing and improve the rate of recurrence.

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Spatio-temporal characterization of ultrashort pulses diffracted by esomeprazole vs omeprazole nhs 24 circularly symmetric hard-edge apertures: theory and experiment. Altered expression and function of ryanodine receptors and FKBP12.6 after subarachnoid hemorrhage: more than meets the eye. The Alhambra (Alh) gene is the Drosophila homologue of the human AF10 gene. The responses to this survey raise important questions about the appropriate use of placebos and the therapeutic value of the placebo effect in clinical practice. Ghrelin, the endogenous ligand for the GHS-R1a, is a 28-amino-acid peptide isolated from human stomach that is modified by a straight chain octanoyl group covalently linked to Ser3, which is essential for its endocrine activity.

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We investigated whether their outgrowths maintain barrier properties of human skin. It has been known that hepatocyte growth factor (HGF) induces gefitinib resistance in non-small cell lung cancer (NSCLC) cells. Comparison of complication rates for unilateral and bilateral percutaneous nephrolithotomy (PCNL) using a modified Clavien grading system. The brain corticotropin-releasing hormone (CRH) circuits are activated by stressful stimuli, contributing to behavioral and why do religions prohibit alcohol emotional responses. Twenty seven of the 39 measured cytokines/chemokines were elevated at 6-12 hours into treatment of DKA compared to values after DKA resolution.

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Both aggregate to insoluble crystals (Hb C) or polymers (Hb S) under certain physiological conditions, impair parasite growth, and may facilitate retention of infected red dicloran tablet use in classroom blood cells (RBCs) in the spleen. The goal of this study was to identify radiographic and anatomic features of Campanacci grade 3 distal radius giant cell tumors that are associated with an acceptable rate of local recurrence after intralesional treatment. We used a fully factorial design and mated females to one, two, three, four or five different males and manipulated conditions so that their offspring received reduced (12 h) or full (ca 72 h) maternal care.

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Toward the development of decision supporting tools that can be used for safe production and use of nanomaterials. The polymorphisms were assessed in 96 individuals from three natural populations (32 individuals per population). This review will compare the effects of NO-3 monoket dosage for amoxicillin availability and PGPB on root morphogenesis and NO-3 uptake, in order to determine whether interactions exist between the NO-3-dependent and the PGPB-dependent regulatory pathways. A cross-sectional survey revealed that serum BDNF levels in chronic schizophrenic patients treated with clozapine exceeded those of patients treated with risperidone or with typical antipsychotics.