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Calan (Verapamil)

Based on our review, 11 prophylactic drugs received a strong recommendation for use (topiramate, propranolol, nadolol, metoprolol, amitriptyline, gabapentin, candesartan, butterbur, riboflavin, coenzyme Q10, and magnesium citrate) and 6 received a weak recommendation (divalproex sodium, flunarizine, pizotifen, venlafaxine, Calan, and lisinopril).

Other names for this medication:
Verapamil, Calan, Calaptin, Isoptin, Verelan,

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Calan is used to treat high blood pressure and to control angina (chest pain). The immediate-release tablets are also used alone or with other medications to prevent and treat irregular heartbeats. Calan is in a class of medications called calcium-channel blockers. It works by relaxing the blood vessels so the heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart and slows electrical activity in the heart to control the heart rate.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

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The maximum body temperature, duration of fever, presence of Koplik spot and exanthema among these adult inpatients were compared with those among 1-to-5-year-old inpatients having measles. Complications such as adhesion formation and tendon rupture can lead to limited hand function.

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We also compared the mean changes in clinical parameters throughout this study between the groups at both time points. Cytotoxic cellular damage against non-myocytes and myocytes was demonstrated using 51Cr-release assay by lymphocytes cultured from myocarditis specimens or splenocytes from mice with chronic CB3 myocarditis.

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Radioactive macrolide accumulation studies pointed to the presence of macrolide efflux in the high-level resistant and parent strains, but not in the hypersusceptible derivative. Locoregional Therapy With Curative Intent Versus Primary Liver Transplant for Hepatocellular Carcinoma: Systematic Review and Meta-Analysis. There was a clear difference between the Holocene floodplains and the Pleistocene terraces, with Holocene floodplain soils being higher in arsenic and other elements. To evaluate high-throughput optical oxygen microrespirometry for selective detection and predictive identification of aerobic bacteria. Furthermore, objective measures of awareness were more readily displayed by individuals with high trait anxiety, whereas individuals with low trait anxiety showed greater access to the experiential quality of happy faces (Experiment 2).

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The antitumour effectiveness of combining the PARP-1 inhibitor before, together and after radiotherapy evidenced the first as the optimal schedule in blocking cell growth. Twelve months after the operation, the tumor recurred in the peritoneal cavity at the site of the stomach, and was associated with multiple liver metastases.

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Our findings substantiate the hypothesis that ANA-positive patients classified into different JIA categories by current ILAR criteria constitute a homogeneous patient population. Gram-negative organisms are slightly less susceptible than gram-positive bacteria. Quantitative phosphoproteomic analysis of prion-infected neuronal cells. We combine a robust timetree based upon multiple fossil calibrations with enhanced biogeographic analyses that include ancestral area reconstructions to provide a detailed biogeographic history of this clade.

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Synthesis and structure-activity relationship studies of cytotoxic vinorelbine amide analogues. Context for Practice: Leakage From the Ostomy Pouch, Constipation in Patients With Colostomies.

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Estimation of lipid peroxidation (LPO) was done by modified method of Utley et al (1967). The significant value of this technique, in combination with virtual autopsy compared with classic autopsy, warrants further evaluation.

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Descriptive statistics were used to answer the research questions. invasion of fibroblastic series cells and small capillaries inside it, were demonstrated. Blood may be safely maintained and used by physicians with little experience in care of major trauma.

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The review ends with a discussion of the safety of this form of exercise and concludes that it is safe and appropriate for most healthy individuals and many of those with different diseases. Some novel sparse reconstruction algorithm has satisfying accuracy and convergence rate, but lose its accuracy for multi-source situation. Syrphid flies are frequent flower visitors, but little is known about the cues they use to find flowers. Skin Treatment with Detergent Promotes Protease Allergen-Dependent Epicutaneous Sensitization in a Manner Different from Tape Stripping in Mice.

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In contrast, in the hippocampus PR induction by E2 was only observed for PR-A. A single, heavily deleted copy of this retrovirus has been found in the genome of miniopterid species, but not in the genomes of the phylogenetically closest bat families, Vespertilionidae and Cistugonidae. Insulin administration, in combination with a multidisciplinary team of health professionals with expertise in the care of patients with CF and CFRD, is the cornerstone of the care for these patients. beta-Lactoglobulin and alpha-lactalbumin form stronger networks and stress propagation is restricted resulting in the growth of irregular (fractal) surfactant domains. The high susceptibility of capillaries to elevated external pressure indicates the necessity of early fasciotomy to restore impaired nutritive circulation in cases of compartment syndrome.

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Coevolution of dynamical states and interactions in dynamic networks. Clinical and histological prognostic factors in locally advanced oral cavity cancers treated with primary surgery. It does not support the classical assumption that spatial heterogeneity in canopy opening explains the coexistence of the two species studied.

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In addition, allele-specificity, a key factor to the success of RNAi-based suppression, was explored with a view to developing a mutation-independent RNAi-based therapeutic for OI by targeting an intragenic SNP within transcripts derived from the COL1A1 gene. The data power measure is tested on both computer generated data and in vivo intrahippocampal electrophysiological recordings from a rat.

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This framework includes seven selection criteria, grouped under five thematic headings: seriousness and extent of the disease burden, effectiveness and safety of the vaccination, acceptability of the vaccination, efficiency of the vaccination, and priority of the vaccination. Implications regarding plastic deformations and reconciling current structural characterizations are discussed. The relationship between acceptance, catastrophizing and illness representations in chronic pain. The success of the predictions is validated by examining the predictions in the context of the three-dimensional structures of protein complexes. NFP-Macs with significant postsurgical tumor residuals contain several DR and SSTR subtypes, some with high copy numbers.

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Center for Inherited Diseases Research-generated genotypes and corresponding phenotypes will be shared with the scientific community through the US National Center for Biotechnology Information database of Genotypes and Phenotypes, and brain MRI studies will be centrally archived. There are several new promising procedures that may have an impact on the early diagnosis of laryngeal precursor lesions.

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These data demonstrate that behavioural status and local environmental conditions interact to affect mechanisms underlying investment trade-offs, presumably in a way that maximizes lifetime reproductive success. Model study of afobazole distribution in pregnant and lactating female rats and infant rat pups The results suggest that the moving camera image sequence introduces an extra level of fatigue and/or distraction to the users. This report describes and compares two new techniques the authors have developed for split earlobe repair: L-specular plasty and double-curve-specular plasty. With an exception of several cases, these searches focused on the cortical feedback exerted onto thalamo-cortical relay (TC) cells of the dorsal lateral geniculate nucleus (LGN).

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High pressure liquid chromatography (HPLC) of tumor tissue confirmed that APMS-MB-DOX particles delivered DOX to target tissue. The severity and progression of the disease were closely monitored with clinical photographs, blood sampling, and tissue biopsies. Further, physicians in general ask more often about IPV now than 5 years ago. Contemporary perspectives on talent identification and development in soccer. Design and evaluation of multi-indicator profiles for targeted-selective treatment against gastrointestinal nematodes at housing in adult dairy cows.

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The top 5 abundant miRNAs identified were miR-202, miR-193b, miR-135a, miR-365, and miR-376a. A Perspective on Ovarian Cancer Biomarkers: Past, Present and Yet-To-Come. Therefore, actual catfish diversity in this region is important to be studied through the combined approach of morphological and molecular technique of DNA barcoding.

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Low-frequency dosing regimens are the best options for long-term HAART with regard to convenience, adherence, and efficacy. The human foramen magnum--normal anatomy of the cisterna magna in adults. In this study we therefore aimed at describing the pattern of neonatal admissions to a Kenyan rural district hospital and their outcome over a 19 year period, examining clinical indicators of inpatient neonatal mortality and also trends in utilization of a rural hospital for deliveries.

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Potential confounders, including perinatal parameters, psychopathology, and use of other substances, were assessed. Pharmacogenetic study of drug-metabolising enzyme polymorphisms on the risk of anti-tuberculosis drug-induced liver injury: a meta-analysis. This study showed that there was an excellent linear relationship between the CR and ACT values and dalteparin concentrations for all the four reagents (glass beads, diatomite, kaolin and magnetic bar) in vitro. Differential expressions of microRNA between young and senescent endothelial cells

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Defined teaching objectives in emergency medicine are now incorporated in undergraduate medical education. Initial experience with robot-assisted nephrectomy for living-donor kidney transplantation: feasibility and technical notes. In expert hands, both transperitoneal and retroperitoneal approaches are feasible, and the choice depends on personal preference.

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To investigate the efficacy of azithromycin in patients with ocular toxoplasmosis. The detection of ELTD1 was also validated in both rodent and human gliomas and may serve as an additional biomarker for gliomas in preclinical and clinical diagnosis of gliomas. Colorectal cancer: chemopreventive role of curcumin and resveratrol.

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Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling. Three different tip designs utilizing an in-plane nano-mechanical tuning approach are shown to achieve reversible and low-loss resonance control on a one-dimensional photonic crystal nanocavity. Estimating the prevalence of dementia using multiple linked administrative health records and capture-recapture methodology. We focused on the incidence, treatment and outcome of osteosarcoma patients.

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Chronic Myeloid Leukemia (CML) is a hematopoietic stem cell malignancy that is driven by the oncogenic BCR-ABL fusion protein, and for which treatment with ABL tyrosine kinase inhibitors (TKI) has yielded great success. Unfortunately, the removal of background bands is not always completely effective. Upregulation of the viability of nucleus pulposus cells by bone marrow-derived stromal cells: significance of direct cell-to-cell contact in coculture system. HPLC microdetermination of flurbiprofen antibiotics for tonsillitis clarithromycin uses enantiomers in plasma with a glycopeptide-type chiral stationary phase column. Individuals exposed to texting within a simulated pedestrian environment reported changes in their intentions to cross streets while distracted and in perceived vulnerability to risk while crossing streets, but we did not witness evidence of changed community norms based on observed rates of distracted pedestrian behavior before and after the intervention compared to a control campus not exposed to the intervention.