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Topamax (Topiramate)

Topamax is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and decrease how often you get them. Topamax will not treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (such as by taking pain medication, lying down in a dark room). Topamax is known as an anticonvulsant or antiepileptic drug.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Topamax is also used for the management of alcohol dependence. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

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Mutual exclusivity of DNA binding and nuclear localization signal recognition by the yeast transcription factor GAL4: implications for nonviral DNA delivery. To assess the feasibility of regional cerebral blood flow measurement by ASL with multiple-delay time sampling in patients with steno-occlusive diseases by comparing with positron emission tomography (PET), and to determine whether regional arterial transit time measured by this ASL technique is correlated with regional mean transit time, a PET index of perfusion pressure.

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This article discusses the role of cyclooxygenase-2 (COX-2) in the aetiology and progression of breast cancer. Locally applied controlled-release doxycycline gel may partly counteract the negative effect of smoking on periodontal healing following non-surgical therapy. Using these sequence tags, we assess similarities and differences between infiltrating T cells in discretely sampled sections of large tumours and compare to T cells from peripheral blood. Autoimmune mechanisms might operate in mice with post-CB3 myocarditis and could be transferred in to SCID mice by the antigen-sensitized lymphocytes. Autologous hemopoietic stem cell transplantation in the treatment of multiple sclerosis: rationale and clinical experience.

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But, in the case of incomplete lung expansion, and/or persistent air leak from CTD, medical or surgical thoracoscopy or, if that is unavailable, limited thoracotomy, should be considered. Panton-Valentine leukocidin (PVL)-negative multilocus sequence type 72 (ST72)-staphylococcal cassette chromosome mec (SCCmec) type IV has been reported as the predominat CA-MRSA strain in Korea and is commonly associated with skin and soft tissue infections in addition to healthcare-associated pneumonia. Lysosomal acid lipase activity was measured using 4-methylumbelliferyl oleate in the leukocytes of an infant suspected of Wolman disease and LIPA gene mutational analysis was performed by PCR and direct sequencing in the proband and his parents. To re-examine ac109 function, we constructed a recombinant AcMNPV bacmid, AcBAC109KO, with a deletion in ac109.

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Moreover, nuclear and cytoplasmic cellular extracts have been showed to be effective in induction of cell differentiation and reprogramming. The DR3 gene duplication measured by FISH was found to be more frequent in patients with RA as compared to healthy individuals. Skeletal muscle development, nutrient uptake, and nutrient utilization is largely coordinated by growth hormone (GH) and its downstream effectors, in particular, IGF-1. Exosomes shift the growth cone morphology to a pro-regenerating phenotype and decrease the activity of the GTPase RhoA, involved in growth cone collapse and axon retraction.

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Expression of several gene products were seen to be increased following in vitro stimulation of human blood eosinophils, including the IL-3 receptor alpha subunit, lymphotoxin beta, Pim-1, and cyclin D3. Acetylation and methylation in nuclear receptor gene activation. However, more extensive evaluations may be necessary to rule out infection and should be considered in those with no contraindications to sedation and in whom other differential diagnoses are also being considered. The traps or phenological indicators can be used by growers to monitor emergence of X. We have previously demonstrated that the asthma-associated proinflammatory eicosanoid leukotriene D4 (LTD4) is co-mitogenic with insulin-like growth factors (IGFs) in airway smooth-muscle (ASM) cells in vitro.

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Usefulness and necessity of the andrologist in assisted reproductions units Sensorimotor Coarticulation in the Execution and Recognition of Intentional Actions. We have recently identified recurrent H3F3A mutations affecting two critical amino acids (K27 and G34) of histone H3.3 in one-third of pediatric GBM.

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The role of alexithymia in expressive incoherence was also assessed. Radiochemotherapy including temozolomide, as established standard therapy for brain malignant astrocytomas, might be valid as a basic therapeutic strategy for this PDLG subtype. Review of available data - particularly from the Global Fund to Fight AIDS, Tuberculosis and Malaria, and the United Nations Joint Programme on HIV/AIDS. Plasma lipids and cellular adhesion molecules were evaluated and peripheral blood flow studies with venous occlusion plethysmography were performed.

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These alterations were found to be in good accordance with tumour stage and were also observed in biopsy samples. Genetic characterization of porcine circovirus-2 field isolates from PMWS pigs. A retrospective cohort study was conducted to estimate the effect of the policy on neonatal outcomes using a before and after design.

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Chemokine receptors and their ligands are involved in a number of cell processes, including normal cell trafficking as well as metastasis in cancer. Findings about involvement of reactive oxygen species (ROS) not only in defense processes, but also in a number of pathologies, stimulated discussion about their role in etiopathogenesis of various diseases. The Daily Record of Severity of Problems is one tool with which women may self-report the presence and severity of premenstrual symptoms that correlate with the criteria for premenstrual dysphoric disorder in the Diagnostic and Statistical Manual of Mental Disorders, 4th ed., text revision. Poor feeding in infants, as well as neurodegeneration, are common phenotypes in human disorders caused by dysfunction of the mitochondrial oxidative phosphorylation system (OXPHOS). We used an heuristic variable selection method and a generalized linear model to classify NAFLD and NASH spectra.

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ADC values as well as conventional MRI parameters were useful in differentiating between benign and malignant STT. We verify this by experimentally irradiating materials of interest in the Cultural Heritage with laser-accelerated protons and measuring the PIXE emission. Data on the effect of hypomyelinating leukodystrophy 6 (HLD6)-associated mutations on the TUBB4A properties. This is a versatile implant which can achieve coupling even in cases of severe middle-ear malformation. A literature search of articles in English, Spanish and Portuguese was conducted in PubMed through September 2011.

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We suggest that the crucial factor for the occurrence of a Garner-interference is whether reaction time is measured such that it actually reflects the total duration of the response selection processes or not. It begins early in the second trimester, and is associated with placental chorangiosis.

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The aim of this study was to determine the prevalence and management of knee joint infection following ACL reconstruction and to assess the functional outcomes. The physical and cell signaling advantages of elastin in a wound healing context creates a parallel with the innate features of fetal skin that can allow for scarless healing. Some may beg to differ: individual beliefs and group political claims.

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Although it is too early to reach broad conclusions, this report of preliminary results confirms the efficacy of DBS of the GPi for cervical dystonia. These data document altered RNA pathways in aging and vitamin E deficiency.

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Forty-five patients underwent the operation via the conventional 4-point, full-sized mesh method, and 42 patients underwent the operation via a novel 2-point, half-sized mesh method. Stones were removed using basket extraction or were fragmented with holmium laser on bench before transplantation. In addition, protocols for the isolation of mitochondria from different tissue sources are provided. We present evidence that this process is the basis of physiological and reparative regeneration of the brain.

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Recent reports underline incidences of the residual influence of neuromuscular blocking agents. Data were from a 21-year follow-up of mothers and their children recruited into the Mater-University of Queensland Study of Pregnancy (MUSP), a longitudinal pre-birth cohort. Interestingly, at the same concentrations statins upregulated VEGF generation in HUVEC. Stage-specific activity of potential antimalarial compounds measured in vitro by flow cytometry in comparison to optical microscopy and hypoxanthine uptake.

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Quantum statistics of a lossless beam splitter: SU(2) symmetry in phase space. It has been demonstrated that the ISO reference procedure fails to detect a significant proportion of coliforms and E. Effect of ventilatory variability on occurrence of central apneas. We therefore examined mouse oocytes exposed for 3 h during fertilization to 50 microg/ml trichlorfon. Prioritizing strategies for comprehensive liver cancer control in Asia: a conjoint analysis.

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High-flexion knee prosthesis was introduced with the aim of obtaining higher degree of flexion and good survivorship in patients with high functional demands or those requiring squatting, kneeling, etc., which is more common in Asians. Experimental results showed that existing single-channel NR algorithms were unable to improve the intelligibility of low-pass filtered Mandarin sentences. Another portion, considerably less than half, exhibits kinetics that are almost exactly the same as in the absence of YC-1. Medical therapy for asymptomatic men with benign prostatic hyperplasia: primum non nocere.

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Treated DC had activated phenotype, reduced phagocytic activity and they induced the proliferation of allogeneic T lymphocytes. Self-reported sensory descriptors are associated with quantitative sensory testing parameters in patients with cervical radiculopathy, but not in patients with fibromyalgia.

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Morphology and biology of each stage are comparatively reviewed. The authors investigated the mechanisms underlying these effects by evaluating the concentration dependence of modulation by enflurane, isoflurane, and halothane of IPSCs in rat hippocampal slices. This study explores patterns of lifestyle change and whether more threatening illness perceptions are associated with lifestyle changes post-treatment for smoking, alcohol consumption and Body Mass Index (BMI) among gynecological cancer patients. There was a significant increase in BBS (6 points) at follow up. Complementary screening techniques yielded fragments that inhibit the phosphatase activity of soluble epoxide hydrolase.

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Modeling Vehicle Collision Angle in Traffic Crashes Based on Three-Dimensional Laser Scanning Data. Placental surface shape, function, and effects of maternal and fetal vascular pathology.

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Care of people with schizophrenia suffers as too much money is spent on secure units. On the other hand, the diffraction peaks of the (012) and (013) planes of untreated creatine monohydrate were much stronger than those of pulverized creatine monohydrate.

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Oral food challenge is the main tool for diagnosing food allergy, but there is little data on the reaction profiles of young children undergoing challenges, nor how these reactions compare to reactions on accidental ingestion in the community. Combined thermal and primary ionization effects on a bacterial virus. In managing the anophthalmic socket, ASOPRS survey respondents preferred to use the porous polyethylene implant after primary enucleation and evisceration. Herein, we demonstrate that the MAPK-activated protein kinase RSK (p90 ribosomal S6 kinase) contributes to melanoma chemoresistance by altering their response to chemotherapeutic agents.

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This paper contributes to the critical review of the literature on EIA implementation and effectiveness by cumulating mainly empirical findings in an implementation theoretical perspective. rubra is frugivorous and dwells in the upper canopy, with notable departures (especially for females) during the hot seasons, gestation, and lactation.

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Twelve of 20 type II diabetic patients were investigated for follow up-study and 6 of those patients were for therapy with Beraprost for diabetic neuropathy. Denaturant gradient gel electrophoresis and 16S rRNA gene pyrotag sequencing revealed that unique mixed biofilm communities were recovered under each incubation condition, with the dominant species belonging to Pseudomonas, Thauera, Hydrogenophaga, Rhodoferax, and Acidovorax. Diagnosis of aGVHD is typically based on clinical symptoms in one or more of the main target organs (skin, liver, gastrointestinal tract) and confirmed by biopsy. Hemodynamic and perioperative management in two different preclinical pig-to-baboon cardiac xenotransplantation models. Riemerella anatipestifer (RA) infections cause major economic losses in the duck industry.

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Condylar movement was slightly different with the two fixation techniques beyond 8 weeks postsurgery, but the ultimate position of the condyle was not different. Currently, data from Switzerland are only available from the University Hospital of Basel. The rate of recovery and the final motor outcome are inversely related to the length of cord involvement. Apoptosis is a key event in APRTP-Js-induced cellular toxicity, but the exact biological mechanisms underlying remain elusive. We offer proofs of PC-corr efficacy on lipidomic, metagenomic, developmental genomic, population genetic, cancer promoteromic and cancer stem-cell mechanomic data.

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The specific normalised values of tissue weighting factors are defined by ICRP for individual tissues, and used as an approximate age- and sex-averaged representation of the relative contribution of each tissue to the radiation detriment of stochastic effects from whole-body low-linear energy transfer irradiations. We propose two experiments that provide diagnostic parameters to monitor the degree of unfolding of a polypeptide. Total error shift patterns for daily CT on rails image-guided radiotherapy to the prostate bed.

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Addition of chia seed mucilage for reduction of fat content in bread and cakes. Working on tillage, drainage and cultivation, the Benedictines not only radically changed the Istrian landscape, reducing the impact and spread of infectious diseases but, through a wise land administration, they also succeeded in creating food supplies for famine periods, which were so frequent in the region.

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The pressure is taken into account in a qualitative, mean field approach, acting on the parameters describing the native stabilizing interactions. We quantified abundance, species richness, evenness, flowering and dominance in relation to biotic and abiotic factors during the growth-, peak-, and recession-phases of the plant growth cycle. It is not clear which RV afterload measure has the greatest impact on RV function and prognosis. Anaerobic threshold (AT) in Fontan patients was lower than in the control subjects.

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Possible alternative treatment options to be considered are to replace the oral capecitabine or intravenous 5-FU by a 5-FU bolus regimen, by uracil-tegafur or tegafur/gimeracil/oteracil, both oral fluoropyrimidines combining a 5-FU prodrug with a dihydropyrimidine dehydrogenase (DPD) inhibitor, or by raltitrexed, a thymidilate synthase inhibitor whose metabolism is independent of DPD. Diet quality tools have been developed to assess the adequacy of dietary patterns for predicting future morbidity and mortality. Treatment with bosentan or ET-A receptor antagonist largely prevented the colitis-induced reduction in blood flow and tissue injury whereas ET-B receptor antagonist did not attenuate tissue injury or reductions in blood flow. The synergistic activation of Raf-1 kinase by phorbol myristate acetate and hydrogen peroxide in NIH3T3 cells.

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AP was associated with: (i) increases in the specific activity of lysosomal enzymes in the soluble fraction, (ii) changes in the size and alterations in the morphology of the organelles from the lysosomal subpopulations, (iii) the appearance of large vacuoles in the primary and secondary lysosome subpopulations, (iv) the increase in the amount of the NAG form associated with the pancreatic lysosomal membrane as well as its release towards the soluble fraction. Analysis of variance, Student t test and the Benjamini-Hochberg multiple testing correction method for multiple testing correction were used to determine the statistical significance of the changes between the three groups.

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The neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest. Radiologic examinations, clinical interviews, physical examinations, and risk factor questionnaires were administered to all the participants.

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The aim of the study was to compare the bone mineral density (BMD) measurements between the patients with polycystic ovary syndrome (PCOS) and age and the body mass index (BMI) matched healthy controls, and to examine whether insulin resistance was associated with BMD. From 34 studies, we obtained 85 effect sizes, based on 12,257 children and adolescents. The suitability of the 2 factors as descriptors of lactation patterns has been confirmed by the relationships found between factor scores and the main environmental effects known to affect the shape of the lactation curve, such as parity and season of calving. Language, culture-specific health interventions and resources and enhancing social support are likely important strategies in promoting chronic disease self-management among the elderly.

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Immunosuppressive and other therapies were carefully adapted to the findings of frequent renal transplant biopsies, which ultimately led to excellent graft function. Subjects with mild and moderate injuries were as likely to use a range of medical and rehabilitation services during the 3-month postdischarge period as those with severe injuries. lugens proxima in all doses of nematode treated plots ranged from 0.42 to 0.48 larvae per plant as against 2.95 larvae / plant in untreated control plots.

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The W-C bond distance for the axial carbonyl group is notably less than those of the equatorial groups. bromazepam compared to clonazepam for anxiety Cumulative exposure to asbestos did not appear to be associated with the incidence of stomach cancer, colorectal cancer or upper aerodigestive cancers. Noninvasive mechanical ventilation in a patient with acute pancreatitis and respiratory failure. PubMed was searched for English-language articles and case reports published from 1977 to 2012.

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Peptic ulcer (PU) and gastroesophageal reflux disease was tacrolimus level adjustment buy diagnosed by endoscopy, and chronic gastritis was determined histologically. Once that capacity is exhausted, a cycle of pathological inflammation ensues and leads to overt disease manifestations. The design controls for changes in case-mix, co-interventions, and secular trends.

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On treatment with brefeldin A (BFA), the homologs co-migrated partly with medial-/trans-Golgi markers and also with a TGN marker in earlier time point, but finally redistributed within cytoplasmic punctate structures that were distinct from medial-/trans-Golgi and the TGN markers. One attractive fender guitar amplifiers india feature of the proposed method is that the four states of the hidden Markov process have well-defined biological meanings and allow us to directly call the change patterns based on the corresponding posterior probabilities. These alterations can affect repeat sequences and cause mutations in coding regions of genes involved in transformation, tumor suppression and apoptosis.

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p63 and p73 are not required for the development and p53-dependent apoptosis of T cells. We hypothesized that the TPS could predict early outcomes in a wide range of diagnoses and age groups. Toward pectin fermentation by Saccharomyces cerevisiae: expression of the first two steps of a bacterial pathway for D-galacturonate metabolism. The endemic status olsar 40 mg side effects of highly pathogenic avian influenza virus (HPAIV) of subtype H5N1 in Egypt continues to devastate the local poultry industry and poses a permanent threat for human health.

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The Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are issuing this interim final rule to amend their regulations to establish new restrictions and modify existing restrictions on the import, capture, transport, sale, barter, exchange, distribution, and release of African rodents, prairie dogs, and certain other animals. Mitochondrial modulation appears to be an important step of the process. Translocations are frequent, clonal and recurrent in mature B cell lymphomas, which bear a particularly high DNA damage burden by virtue of activation-induced cytidine deaminase (AID) expression. Ablation of smooth penile thrombosis ibuprofen during pregnancy muscle caldesmon affects the relaxation kinetics of arterial muscle.

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To clone novel metastasis-associated genes of colorectal carcinoma and provide clues for the molecular mechanisms of metastasis of colorectal carcinoma. Compressive sensing of foot-gait signals by enhancing group block-sparse structure on the first-order difference. Hypoglossal-facial anastomosis (HFA) is a cross-over between the proximal stump of the hypoglossal nerve (XII) and cardivas 6.25 side effects the distal one of the facial nerve (VII).

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This study supports the importance of a continuing emphasis on preventing back and sharps injuries and reducing risks faced by aides in the hospital setting. Conversely, corticosteroids are the drug of choice to treat polymyalgia rheumatica. Novel immunotherapeutic strategies in development for renal cell carcinoma. We conclude that the brain contains high abundance nonclassical binding sites for cocaine-like drugs that have micromolar affinity for cocaine and that none of the clinically available amphetamine-type appetite suppressants are equipotent substrates for dopamine transporter (DAT) and serotonin transporter (SERT) proteins. Both seizures and antiepileptic omeprazole dr 20mg ingredients treatments may lead to short term complications and worsen the outcomes.

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Urinary L-FABP and its combination with urinary NGAL in early diagnosis of acute kidney injury zithromax 1000mg prophylactic dose of acyclovir after cardiac surgery in adult patients. The prevalence of AF may be low in this population owing to premature cardiovascular death.

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Radiation-induced fibrosarcoma after radiotherapy for osteosarcoma in the mandibular condyle. Principles in the treatment of infections of the soft parts of the palmar surface of the hand and fingers These tumor cells contain spectrosomes characteristic of ovarian germ-line stem cells and the immediate descendents called cystoblasts. Contact with the monolitum 15 mg precio del bristles causes symptoms of acute inflammation.

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We suggest that the presence of large numbers of rhesus macaques in anthropogenic ketoconazole shampoo perfect image areas in south-eastern India is not a natural phenomenon but has been caused by human intervention. CR expression was determined by flow cytometry and their functional activity by migration to chemoattractants.

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Culturally effective pediatric care: education and training issues. Differential modulation of corticospinal excitability during observation, mental imagery and imitation of hand actions. A suite of geospatial data were acquired for Philadelphia, including 1,964 alcohol outlet locations, 569,928 land parcels, and school, church, amoxicillinum 500 mg dawkowanie augmentin hospital, park and playground locations. Two independent series of experiments have been conducted during three years in the same laboratory.

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We sought to investigate the clinical impact of such reporting in the treatment of patients with suspected acute coronary syndrome (ACS). A selected screening programme was less effective in the detection of methicillin-resistant Staphylococcus aureus colonisation in an orthopaedic unit. The sensitive to freezing2-1 (sfr2-1) mutation causes freezing sensitivity in Arabidopsis thaliana. Organic extracts from a control standard soil (Lufa 2.2) had negligible effects on expression of these genes, and similarly several pesticides had little effect ticn vs altin shira on the expression of a constitutive myo-3::GFP transgene. As damage to the kidney is easy to measure by monitoring albuminuria and eGFR, and as the early phases of kidney damage frequently precede the alarming symptomatology in the heart, brain and peripheral vasculature, we argue that the nephrologist should consider taking the lead in better organizing early detection and management of CKD.